Homocysteine, Folate, and Cognitive Domains

Cognitive
Function Test
Cognitive DomainMaintenance
3MSE Global ↑Folate
↓Homocysteine
Delayed Recall Short Term Memory ↑Folate
Object Naming Language
Picture Association Long Term Memory ↓Homocysteine
Verbal Conceptual ThinkingExecutive Function
Verbal Attention Attention ↓Homocysteine
Pattern Recognition Visuospatial Skills↓Homocysteine

Miller et al, Am J Clin Nutr, 2003
Ramos et al, Am J Clin Nutr, 2005